Sterilisation is the term commonly used for when pets have a surgery  to remove part of their reproductive tract, making them unable to breed. Whilst most cats and dogs are sterilized, the procedure is often overlooked in small pet mammals, such as rabbits, guinea pigs, ferrets and rats. This handout discusses the advantages and disadvantages of desexing in ferrets, and why surgical desexing may not be the best option for every ferret.

What are the different types of sterilisation?

The most common form of sterilisation is when an animal undergoes surgery to remove part of their reproductive tract. However, in ferrets there is a medical approach to sterilization. This is temporary but can last 1-2 years depending on the individual ferret’s response.  In ferrets these medical alternatives have some benefits over surgical desexing and are recommended for many ferrets, particularly those under the age of 2 years.

Is surgical or medical sterilization better for my ferret?

FerretsSurgical desexing in ferrets is considered a routine procedure and removes parts of the reproductive tract that can be prone to developing tumours later in life. However, like any procedure involving general anaesthesia, there are some risks. Medical sterilization avoids the risk of a longer general anaesthetic and can often be given in conscious ferrets. This involves a small implant being placed between your ferret’s shoulders. The implant is known as Deslorelin (Suprelorin®) and is a widely available medication in Australia, due to its use in dogs.

The main advantage of medical sterilization is that it reduces the risk of adrenal disease developing in ferrets.

What is adrenal disease in ferrets?

Adrenal disease is a term used to describe a change to the adrenal glands, which can be cancerous. This has been linked to early surgical sterilization in ferrets, particularly those that are desexed before 6 months of age. Medical forms of sterilization avoid the risk of adrenal disease by leaving the ovaries and testicles in place.



What if I choose not to sterilize my ferret?

Ferret dentalWhichever form of sterilization you choose, it is still recommended to get your ferret sterilized for several reasons:  

  • Many female ferrets (approximately 50%) are unable to come out of heat (oestrus) without a vasectomized or entire male present. If jills stay in heat they can develop a condition known as oestrogen toxicity, which causing life-threatening anaemia. Desexed ferrets to not develop this problem.
  • Whilst both male and female ferrets both have a characteristic smell, it is the entire male ferrets that are known for their stronger, more pungent odour. Both surgical and medical sterilization can significantly reduce this smell.
  • Sterilisation can also reduce certain behaviours such as aggression and urine marking.

What is the difference in cost between medical and surgical sterilization?

The cost of each is similar. The main advantage of surgical sterilisation is that it is a one-off cost whereas the deslorelin implant needs to be repeated every 12-18 months.


 Surgical sterilisationMedical sterilization (Deslorelin)
Is an anaesthetic required?YesIn some cases – depends on the ferret
Does it need to be repeated?NoYes, every 1-1.5 years
Does it work for both sexes?YesYes
Is the procedure linked to a potentially higher risk of adrenal disease developing in later years?YesNo
Does it prevent pregnancy?YesYes
Does it prevent reproductive diseases such as tumours?YesNo

Where can I get more information on ferret desexing?

The Unusual Pet Vets are available to provide information by email, phone call or by booking a consult. Our website www.unusualpetvets.com.au also has many helpful articles about ferret health, as well as further contact information for each of our clinics.